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GLOSSARY
HICA (LEUCIC ACID)

HICA (leucic acid)

 

How does it work?

HICA, chemically known as alpha-hydroxyisocaproic acid, is a metabolite of the branched chain amino acid leucine.1 HICA is thought to have anti-catabolic and anabolic activity, as well as reducing delayed onset of muscle soreness (DOMS) after intensive exercise.2 This was seen in a study using soccer athletes undergoing routine exercise protocols over a 4 week period, resulting in small increases in muscle mass and reduction in DOMS compared to placebo.3

What results can be expected?

HICA supplementation may assist in reducing muscle soreness after intensive exercise regimes, as well as minorly increasing muscle mass, however more research is needed to confirm these benefits for all individuals.4

1Frank, K. (2014). Supplements. Retrieved Feb 2014, from Examine.com: http://examine.com/supplements/Leucic+Acid/

2Mero, A et al. (2010). Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes. J Int Soc Sports Nutr, 7(1). Retrieved Feb 2014, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818616/

3Mero, A et al. (2010). Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes. J Int Soc Sports Nutr, 7(1). Retrieved Feb 2014, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818616/

4Mero, A et al. (2010). Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes. J Int Soc Sports Nutr, 7(1). Retrieved Feb 2014, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818616/