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GLOSSARY
GRAPEFRUIT EXTRACT

Grapefruit Extract

 

How does it work?

Grapefruit extract refers to the juice, peel or pectin of the grapefruit, however excludes use of the seed which exerts different biological effects.1 Grapefruit juice is used for its antioxidant, lipid and cholesterol lowering effects, as well as its ability to influence insulin resistance and weight loss.2 3 Grapefruit pectin has also shown to reduce high cholesterol and provide protection against atherosclerosis.4 It is also important to note that grapefruit juice is known to interact with the metabolism of certain medications, therefore consumption or supplementation of grapefruit should be monitored by a health professional if taking medications.5

What results can be expected?

Grapefruit extract may assist with lowering high cholesterol and triglycerides.6 Using grapefruit extract as an adjunct treatment to a weight reduction diet may assist with weight loss and insulin resistance.7 Grapefruit consumption should be monitored if taking medications.8

1WebMD. (2009). Vitamins and Supplements - Grapefruit. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-946-grapefruit.aspx?activeIngredientId=946&activeIngredientName=grapefruit

2Gorinstein, S et al. (2005). Changes in Plasma Lipid and Antioxidant Activity in Rats as a Result of Naringin and Red Grapefruit Supplementation. J. Agric. Food Chem, 53(8), 3223-28. Retrieved Feb 2014, from http://pubs.acs.org/doi/abs/10.1021/jf058014h

3Fujioka, K et al. (2006). The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome. J Med Food, 9(1), 49-54. Retrieved Feb 2014, from http://www.ncbi.nlm.nih.gov/pubmed/16579728

4Baekey, B et al. (1988). Grapefruit pectin inhibits hypercholesterolemia and atherosclerosis in miniature swine.Clinical Cariology, 11(9), 595-600. Retrieved Feb 2014, from http://onlinelibrary.wiley.com/doi/10.1002/clc.4960110903/abstract

5WebMD. (2009). Vitamins and Supplements - Grapefruit. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-946-grapefruit.aspx?activeIngredientId=946&activeIngredientName=grapefruit

6Baekey, B et al. (1988). Grapefruit pectin inhibits hypercholesterolemia and atherosclerosis in miniature swine.Clinical Cariology, 11(9), 595-600. Retrieved Feb 2014, from http://onlinelibrary.wiley.com/doi/10.1002/clc.4960110903/abstract

7Fujioka, K et al. (2006). The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome. J Med Food, 9(1), 49-54. Retrieved Feb 2014, from http://www.ncbi.nlm.nih.gov/pubmed/16579728

8WebMD. (2009). Vitamins and Supplements - Grapefruit. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-946-grapefruit.aspx?activeIngredientId=946&activeIngredientName=grapefruit