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GLOSSARY
4-DIHYDROXYCINNAMIC ACID (CAFFEIC ACID)

4-Dihydroxycinnamic Acid (Caffeic Acid)

 

How does it work?

Caffeic acid is a phenolic acid that is naturally occurring in many plants foods such as green and roasted coffee beans and wine.1 2 It is known to be a potent antioxidant3 and is an inhibitor of the enzymes DOPA-decarboxylase and 5-lipoxygenase giving it analgesic and anti-inflammatory properties.4 In vivo studies have shown that the antioxidant property of caffeic acid provides cardio-protective effects against dyslipidaemia, hypercoagulability, oxidative stress and inflammation.5

What results can be expected?

Caffeic acid may provide triglyeride-lowering, anti-coagulatory and anti-inflammatory protection in cardiac tissue due to its potent antioxidant and free radical scavenging activity.6 Other studies have also shown caffeic acid to have a mild stimulant effect and reduce exercise-related fatigue.7

1Chao, P. (2009). Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutrition and Metabolism, 6, 33. Retrieved Jan 2014, from http://www.nutritionandmetabolism.com/content/6/1/33

2Pengelly, A. (2004). The Constituents of Medicinal Plants (2nd ed.). Crows Nest: Allen and Unwin pp.17

3Gulcin, I. (2006). Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid). Toxicology, 217(2-3), 213-220. Retrieved Jan 2014, from http://www.sciencedirect.com/science/article/pii/S0300483X05004786

4Pengelly, A. (2004). The Constituents of Medicinal Plants (2nd ed.). Crows Nest: Allen and Unwin pp.17.

5Chao, P. (2009). Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutrition and Metabolism, 6, 33. Retrieved Jan 2014, from http://www.nutritionandmetabolism.com/content/6/1/33

6Chao, P. (2009). Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutrition and Metabolism, 6, 33. Retrieved Jan 2014, from http://www.nutritionandmetabolism.com/content/6/1/33

7WebMD. (2009). Vitamins and Supplements - Caffeic Acid. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-1266-CAFFEIC%20ACID.aspx?activeIngredientId=1266&activeIngredientName=CAFFEIC%20ACID